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No.IF you are an agent and you get an email from osTicket and you reply it,,, it updates the ticket as an internal note. Internal notes are not sent to the owner of the ticket, as they are internal.Otherwise yes everything must be done from within osTicket. Unless you change the behavior of the paragraph above (which is possible and other people here on the forums have posted about doing).I rarely email the ticket system because I want my response to go to the User (client). So I log into osTicket and do it.