Thank you so much for your time, thoughts, and suggestions, @[deleted] I really appreciate it! I'm on a shared hosting package with HostGator, so I don't think they will let me install software on the server, but I'll look into the options. I'll also look at a re-install. In the mean time... if anyone had any other suggestions of what to try, I would be most grateful. 

I went back through the download folder, and I see there is a "scripts" folder with files: -api_ticket_create.php-automail.php-automail.pl-rcron.phpThe installation section of the wiki doesn't mention this folder or files. Are any of these important to these issues I am having?They seem to be scripts to use via the api for running things from a remote server, but I could be wrong. 

I found this ancient post:http://forums.hostgator.com/help-ostickets-fantastico-t1508.htmlI didn't know if you saw this either:IMPORTANT NOTE REGARDING USE OF EXTERNAL SMTP SERVERSSome hosting companies (Hostgator.com, for example) do not allow the use of SMTP servers located on a separate server and will block all requests. Trying to connect to a blocked external SMTP server will result in a "login failure" message in OSTicket when trying to save the Outgoing Emails settings.

http://osticket.com/wiki/Email_settings (Yes, I know you said the Diagnostic email works.)

Thanks! I do have the mail piping working with the chmoding of pipe.php. It seems to me the automail.php and automail.pl are for setting up an external SMTP. (Let me know if I am wrong on this detail) and is only triggered when an email is incoming. I am aware of the Important Note, however I don't have any external SMTP servers. The osTicket installation and the mail server are all on the same server with HostGator. I don't get any errors when setting up the SMTP for outgoing. As far as I can tell, I've followed every instruction in the "Email_settings" page. Thanks so much for the additional info. At this point it's possible anything might trigger the answer. Also, Let me know if I'm not understanding what you are sharing with me.

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