Sure. I simply forwarded email from mailbox where the support requests came into. This was setup on 365 (obviously), but before I could turn on forwarding I had to enable it on my tenant, it seems to be turned off by default - you can enable a rule for an individual mailbox or all users here: https://protection.office.com/antispam
Once the email was forwarding I reconnected osticket to the new simple mailbox which allowed pop3 collection.