Kratos,
Setting up a cron job in cPanel is pretty straightforward. For what you need to do, simply click on the cron jobs icon and then select "standard" and in the "command to run" box, enter
nobody /path/to/php /path/to/api/cron.php
Updating your paths accordingly. PHP is usually in /usr/bin/php but that may vary depending on your server configuration. if you're not sure where to find it, check with your server administrator.
Then select "every 5 minutes" and click OK.
You can read up more about setting up cron and how it works here:
http://osticket.com/wiki/POP3/IMAP_Settings(http://osticket.com/wiki/POP3/IMAP_Settings)
Better yet, you can forego cron all together and use email piping. Instructions for configuring that can be found here:
http://osticket.com/wiki/Email_Piping(http://osticket.com/wiki/Email_Piping)
Or you could simply enable auto-cron, which functions similarly to a standard cron job, but is activated based on staff activity and not an actual cron job.