I can't figure out where I can explicitly enable and / or configure sending notification emails to the user when a ticket changes status.

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There is no "change status" alert/notification. You're agent would select a Canned Response when they change the status. (Reply)

    Thanks for your reply ntozier

    So the only notification the ticket owner receives after opening the ticket is from reply posts?

    You can see the User alerts by going to:
    Admin panel -> Settings -> Tickets -> Autoresponder

    New Ticket
    New Ticket by Agent
    New Message
    Overlimit Notice

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