vershare
The zip and Zend opcache errors are simply saying you are missing the PHP zip and Zend opcache extensions. You can install and enable them on the server and you should be good. You may need to restart your web server and PHP-FPM (if you’re running it) after doing so to ensure the changes are applied.
As for the cgi.fix_pathinfo error that’s only needed if AJAX is not working. To tell if AJAX is working or not you can simply click something like Advanced Search or any Ticket action and if the popup loads and works then you don’t need to fix this.
Lastly, the auto responder and alerts are controlled by a few settings. Here is the documentation:
Cheers.