manmach
I'm running an almost identical setup on Ubuntu but my PHP is 8.1.9 and MySQL is 8.0.30; but this doesn't really matter. Anyways, I cannot replicate the same issue. Can you review your logs (general server logs, webserver error logs, PHP error logs, MySQL/MariaDB error logs, osTicket System Logs, Browser Console logs, etc.) for any related errors?
Cheers.